Serum markers of liver fibrosis
نویسندگان
چکیده
منابع مشابه
Molecular Serum Markers of Liver Fibrosis
Fibrosis is a hallmark histologic event of chronic liver diseases and is characterized by the excessive accumulation and reorganization of the extracellular matrix (ECM). The gold standard for assessment of fibrosis is liver biopsy. As this procedure has various limitations, including risk of patient injury and sampling error, a non-invasive serum marker for liver fibrosis is desirable. The inc...
متن کاملNon-invasive Assessment of Liver Fibrosis Using Serum Markers
Fibrosis is an intrinsic response to chronic injury, that elicits excess deposition of matrix compounds and scarring, which ultimately alters liver structure and function. Liver biopsy has long been the gold standard for assessing the degree of liver fibrosis. Due to liver biopsy invasiveness, specialists and patients favor alternative non-invasive tests for fibrosis staging. In recent years, m...
متن کاملSystematic review of the diagnostic performance of serum markers of liver fibrosis in alcoholic liver disease
BACKGROUND Alcoholic liver disease (ALD) is a significant cause of death and morbidity. Detection of liver fibrosis at an early stage could provide opportunities for more optimal management. Serum markers of liver fibrosis offer an alternative to biopsy. Evidence of the performance of biomarkers in ALD is needed and a systematic review to evaluate available studies was conducted. METHODS Elec...
متن کاملPrediction of Post-Operative Liver Dysfunction by Serum Markers of Liver Fibrosis in Hepatocellular Carcinoma
AIM To investigate the role of biomarkers in predicting postoperative liver dysfunction in patients with hepatocellular carcinoma (HCC). METHODS A total of 200 patients operated from July 2009 to June 2010 at Zhongshan Hospital, Fudan University for pathologically confirmed HCC were retrospectively analyzed for clinical data, HBD DNA level and serum biochemical markers for liver fibrosis. The...
متن کاملSerum Liver Fibrosis Markers in the Prognosis of Liver Cirrhosis: A Prospective Observational Study
BACKGROUND The prognostic role of serum liver fibrosis markers in cirrhotic patients remains unclear. We performed a prospective observational study to evaluate the effect of amino-terminal pro-peptide of type III pro-collagen (PIIINP), collagen IV (CIV), laminin (LN), and hyaluronic acid (HA) on the prognosis of liver cirrhosis. MATERIAL AND METHODS All patients who were diagnosed with liver c...
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ژورنال
عنوان ژورنال: Kanzo
سال: 2018
ISSN: 0451-4203,1881-3593
DOI: 10.2957/kanzo.59.377